List of substrates found:


Substrate: AIM-1 (Ser/Thr protein kinase family. Aurora subfamily)
Seq-ID: Q96GD4 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-65645   ANKZ1_HUMAN
MINT-77928   INCE_HUMAN
MINT-4509558   BIRC5_HUMAN
MINT-6166761   RGAP1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
metal ion binding,
ATP binding,
protein binding		 spindle,
chromosome passenger complex,
cytoplasm,
condensed nuclear chromosome, centromeric region		 protein amino acid phosphorylation,
protein localization to kinetochore,
mitosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 232 SVHAPSLRRKTMCGTLDYLPP Aurora B 14722118
LTP
1.00
 - S_TKc
0.22
 - low

Substrate: Apoptosis inhibitor survivin (Adapter molecule)
Seq-ID: O15392 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-77929   INCE_HUMAN
MINT-4055407   XPO1_HUMAN
MINT-4509524   BOREA_HUMAN
MINT-4509558   AURKB_HUMAN
MINT-7969366   BECN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cobalt ion binding,
cysteine-type endopeptidase inhibitor activity,
protein heterodimerization activity,
identical protein binding,
protein homodimerization activity,
metal ion binding,
cofactor binding,
caspase inhibitor activity,
Ran GTPase binding,
microtubule binding,
chaperone binding,
zinc ion binding		 spindle,
chromosome, centromeric region,
midbody,
chromosome passenger complex,
spindle microtubule,
cytoplasm,
cytosol,
centriole,
cytoplasmic microtubule,
interphase microtubule organizing center,
nuclear chromosome		 cytokinesis,
positive regulation of mitotic cell cycle,
apoptosis,
anti-apoptosis,
chromosome segregation,
establishment of chromosome localization,
negative regulation of caspase activity,
positive regulation of exit from mitosis,
mitosis,
spindle checkpoint,
G2/M transition of mitotic cell cycle,
protein complex localization,
cell division
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 117 ERAKNKIAKETNNKKKEFEET Aurora B 14610074
LTP
0.68
 - COIL
0.56
 2RAW 50.68%

Substrate: Centromeric protein a (DNA binding protein)
Seq-ID: P49450 [Homo sapiens]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7243462   ABL1_HUMAN
MINT-7245910   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
chromatin binding,
protein binding		 condensed nuclear chromosome kinetochore,
nucleosome		 nucleosome assembly,
kinetochore assembly,
establishment of mitotic spindle orientation,
protein localization to chromosome, centromeric region,
interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 7     MGPRRRSRKPEAPRRRS Aurora B 11756469
LTP
0.00
 - -
0.94
 - medium

Substrate: Desmin (desmin (from PhosphoBase))
Seq-ID: P17661 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural constituent of cytoskeleton,
protein binding		 Z disc muscle contraction,
regulation of heart contraction,
cytoskeleton organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 12 SQAYSSSQRVSSYRRTFGGAP Aurora B 12686604
LTP
0.85
 - Filament_head
0.44
 - medium
T 17 SSQRVSSYRRTFGGAPGFPLG Aurora B 12686604
LTP
0.25
 - Filament_head
0.45
 - medium
S 60 TSRVYQVSRTSGGAGGLGSLR Aurora B 12686604
LTP
0.98
 - Filament_head
0.44
 - medium

Substrate: GFAP (glial fibrillary acidic protein, astrocyte (GFAP) (from PhosphoBase))
Seq-ID: P14136 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-66480   PDLI1_HUMAN
MINT-66672   PDLI7_HUMAN
MINT-66894   VIME_HUMAN
MINT-68330   CEP76_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural constituent of cytoskeleton intermediate filament,
cytoplasm
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 7     MERRRITSAARRSYVSS Aurora B 12686604
LTP
0.10
 - Filament_head
0.47
 - low
S 13 RRRITSAARRSYVSSGEMMVG Aurora B 12686604
LTP
0.38
 - Filament_head
0.42
 - low
S 38 GRRLGPGTRLSLARMPPPLPT Aurora B 12686604
LTP
0.88
 - Filament_head
0.63
 - low

Substrate: GTPase activating protein (Unclassified)
Seq-ID: Q9H0H5 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50978   1433B_HUMAN
MINT-61542   GRB2_HUMAN
MINT-3975200   1433S_HUMAN
MINT-6166634   ECT2_HUMAN
MINT-6166653   PP2AA_HUMAN
MINT-6166761   AURKB_HUMAN
MINT-6166774   CDC2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein C-terminus binding,
beta-tubulin binding,
metal ion binding,
GTPase activator activity,
alpha-tubulin binding,
gamma-tubulin binding		 spindle,
midbody,
acrosomal vesicle,
nucleus,
microtubule		 sulfate transport,
signal transduction,
spermatogenesis,
cytokinesis, initiation of separation,
cytokinesis, actomyosin contractile ring assembly,
neuroblast proliferation,
embryo development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 387 GLTETGLYRISGCDRTVKELK Aurora B 12689593
LTP
0.96
 - RhoGAP
0.22
 2OVJ 79.51%
S 410 FLRVKTVPLLSKVDDIHAICS Aurora B 15108802
LTP
0.23
 - RhoGAP
0.07
 2OVJ 65.57%

Substrate: Histone H3.1 (Histone H3)
Seq-ID: P68431 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50057   UHRF1_MOUSE
MINT-61561   GRB2_HUMAN
MINT-2829033   CBX1_HUMAN
MINT-2829698   KDM4A_HUMAN
MINT-2830038   CDYL1_HUMAN
MINT-2830062   PHF20_HUMAN
MINT-2830088   TP53B_HUMAN
MINT-2830965   CBX5_HUMAN
MINT-2831013   CBX3_HUMAN
MINT-6665460   BRD7_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
protein binding		 nucleus,
nucleosome		 nucleosome assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 15108802
LTP
0.87
 - -
0.78
 - medium
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 12082625
LTP
0.87
 - -
0.78
 - medium
S 29 KQLATKAARKSAPATGGVKKP Aurora B 12082625
LTP
0.62
 - -
0.65
 - medium

Substrate: Histone H3.3 (DNA binding protein)
Seq-ID: P84243 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7297192   CBX5_HUMAN
MINT-7297230   DNM3A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding nucleus,
nucleosome		 nucleosome assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 14722118
LTP
0.76
 YWHAG 14-3-3;
YWHAZ 14-3-3		 -
0.79
 - medium
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 11856369
LTP
0.76
 YWHAG 14-3-3;
YWHAZ 14-3-3		 -
0.79
 - medium
S 29 KQLATKAARKSAPSTGGVKKP Aurora B 14722118
LTP
0.70
 YWHAG 14-3-3 -
0.70
 - medium
S 29 KQLATKAARKSAPSTGGVKKP Aurora B 11856369
LTP
0.70
 YWHAG 14-3-3 -
0.70
 - medium

Substrate: Histone H3.3 (DNA binding protein)
Seq-ID: P84244 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding nucleus,
nucleosome		 nucleosome assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 16179389
LTP
0.76
 - -
0.79
 - low
S 11 MARTKQTARKSTGGKAPRKQL Aurora B 11784863
LTP
0.76
 - -
0.79
 - low

Substrate: Hypothetical protein rec-8 (Unclassified)
Seq-ID: W02A2.6 [Caenorhabditis elegans]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-21393   Q19555_CAEEL
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding synaptonemal complex,
nuclear chromatin		 synaptonemal complex assembly,
reciprocal meiotic recombination,
embryo development ending in birth or egg hatching,
double-strand break repair,
meiotic chromosome movement towards spindle pole
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 625 LFPTPEKRRETSIIAELNLDP Aurora B 15108802
LTP
 - - -
0.50
 - medium
S 626 FPTPEKRRETSIIAELNLDPI Aurora B 15108802
LTP
 - - -
0.53
 - medium

Substrate: Inner centromere protein (Cell cycle control protein)
Seq-ID: Q9NQS7 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-77928   AURKB_HUMAN
MINT-77929   BIRC5_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding spindle,
condensed chromosome kinetochore,
cytoplasm,
centromeric heterochromatin,
microtubule		 cytokinesis,
chromosome segregation,
mitosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 897 KKSKPRYHKRTSSAVWNSPPL Aurora B 12925766
LTP
0.00
 - -
0.57
 - medium
S 898 KSKPRYHKRTSSAVWNSPPLQ Aurora B 12925766
LTP
0.29
 - -
0.58
 - medium
S 899 SKPRYHKRTSSAVWNSPPLQG Aurora B 12925766
LTP
1.00
 - -
0.59
 - medium

Substrate: KIF2C (centromeric DNA binding, microtubule motor activity)
Seq-ID: P70096 [Cricetulus griseus]
Download:fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
microtubule plus-end binding,
microtubule motor activity,
ATP binding		 condensed chromosome kinetochore,
cytoplasm,
nucleus,
microtubule		 cell division,
chromosome segregation,
regulation of chromosome segregation,
microtubule-based movement,
mitosis,
microtubule depolymerization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 92 NVTVPKQKRRSVNSKIPAPKE Aurora B 14960279
LTP
0.09
 - -
0.71
 - medium

Substrate: KIF2C (centromeric DNA binding, microtubule motor activity)
Seq-ID: Q91636 [Xenopus laevis]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
microtubule motor activity,
ATP binding		 condensed chromosome kinetochore,
cytoplasm,
nucleus,
microtubule		 cell division,
chromosome segregation,
microtubule-based movement,
mitosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 95 NVSSQNHKRKTISKIPAPKEV Aurora B 17567953
LTP
0.00
 - -
0.73
 - medium
S 110 PAPKEVAAKNSLLSESGAQSV Aurora B 17567953
LTP
 - - -
0.60
 - medium
S 177 AEEPRLQTRISEIVEESLPSG Aurora B 15064354
LTP
0.11
 - -
0.64
 - medium
S 196 SGRNNQGRRKSNIVKEMEKMK Aurora B 14972678
LTP
1.00
 - COIL
0.79
 - medium
S 196 SGRNNQGRRKSNIVKEMEKMK Aurora B 17567953
LTP
1.00
 - COIL
0.79
 - medium

Substrate: KIF2C (centromeric DNA binding, microtubule motor activity)
Seq-ID: Q99661 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-7256324   MARE1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
microtubule plus-end binding,
centromeric DNA binding,
microtubule motor activity,
ATP binding		 condensed chromosome kinetochore,
cytoplasm,
nucleus,
microtubule,
kinesin complex		 cell division,
chromosome segregation,
regulation of chromosome segregation,
microtubule-based movement,
mitosis,
microtubule depolymerization,
establishment or maintenance of microtubule cytoskeleton polarity,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 95 NVTIQKQKRRSVNSKIPAPKE Aurora B 14960279
LTP
0.15
 - -
0.65
 - medium

Substrate: Kinesin-like protein KIF23 (ATPase)
Seq-ID: Q02241 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50975   1433B_HUMAN
MINT-3318708   1433Z_HUMAN
MINT-3975708   1433S_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
microtubule motor activity,
ATP binding,
protein binding		 spindle,
midbody,
cytoplasm,
nucleoplasm,
microtubule,
kinesin complex		 cell division,
mitotic spindle elongation,
microtubule-based movement,
mitosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 714 LMSQPQLHRRSNSCSSISVAS Aurora B 15854913
LTP
 - - -
0.49
 - medium

Substrate: Myosin regulatory light chain 2, smooth muscle isoform
Seq-ID: Q64122 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
calcium ion binding,
motor activity		 myosin complex
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 20 TTKKRPQSATSNVFAMFDQSQ Aurora B 11098131
LTP
1.00
 - -
0.53
 - medium

Substrate: Vimentin (vimentin (from PhosphoBase))
Seq-ID: P08670 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-48218   NEMO_HUMAN
MINT-48335   M3K1_HUMAN
MINT-48490   M3K3_HUMAN
MINT-48555   NFKB1_HUMAN
MINT-49072   RIPK2_HUMAN
MINT-49446   TNR1B_HUMAN
MINT-51249   SMAD3_HUMAN
MINT-63478   FABP4_HUMAN
MINT-63483   CREB1_HUMAN
MINT-63519   SYN1_HUMAN
MINT-64054   RAD51_HUMAN
MINT-64131   TIF1B_HUMAN
MINT-64137   NFAC2_HUMAN
MINT-64185   CASP8_HUMAN
MINT-64286   STX1A_HUMAN
MINT-64820   Q86V38_HUMAN
MINT-64930   SIRT6_HUMAN
MINT-64945   CA103_HUMAN
MINT-64988   PAIRB_HUMAN
MINT-65109   FUBP1_HUMAN
MINT-65490   TARA_HUMAN
MINT-65741   PUF60_HUMAN
MINT-65855   SRRT_HUMAN
MINT-65878   NS1BP_HUMAN
MINT-66105   MYST2_HUMAN
MINT-66208   ABLM1_HUMAN
MINT-66844   K1C20_HUMAN
MINT-66894   GFAP_HUMAN
MINT-67503   PDLI1_HUMAN
MINT-67553   PSA1_HUMAN
MINT-67944   GOPC_HUMAN
MINT-2515544   SYUA_HUMAN
MINT-2791056   RD23A_HUMAN
MINT-2791422   RD23B_HUMAN
MINT-2985160   ZO1_HUMAN
MINT-3297793   1433Z_HUMAN
MINT-3979536   CHD3_HUMAN
MINT-3979774   ZHX1_HUMAN
MINT-3980301   SETB1_HUMAN
MINT-3980318   NFL_HUMAN
MINT-3980438   ING5_HUMAN
MINT-3980472   PPHLN_HUMAN
MINT-3980489   UT14A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein C-terminus binding,
structural constituent of cytoskeleton		 intermediate filament,
cytosol		 cellular component movement,
interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 73 TRSSAVRLRSSVPGVRLLQDS Aurora B 12458200
LTP
0.87
 - Filament_head
0.38
 --
S 73 TRSSAVRLRSSVPGVRLLQDS Aurora B 15676024
LTP
0.87
 - Filament_head
0.38
 --

Substrate: Vimentin (vimentin (from PhosphoBase))
Seq-ID: P20152 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19723   ARRB1_HUMAN
MINT-50699   KPCE_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytoplasm,
type III intermediate filament,
cell leading edge		 intermediate filament-based process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 73 TRSSAVRLRSSVPGVRLLQDS Aurora B 12458200
LTP
0.85
 - Filament_head
0.38
 - medium

Valid HTML 4.01 Transitional